Tuesday, December 2, 2014

Recalcitrant Psoriasis Treated Effectively with Apitherapy

Apitherapy is the use of one or more products from honey bees to heal or prevent diseases. This abstract doesn't specify which bee products were used, but individual studies concerning the dermatological therapeutic effects of propolis, honey, royal jelly and bee venom are numerous. In general, studies in Apitherapy show a 'synergistic effect' when multiple bee products are combined, providing a more potent solution.

Efficacy of the Apitherapy in the treatment of recalcitrant localized plaque psoriasis and evaluation of tumor necrosis factor-alpha (TNF-α) serum level: a Double blind randomized clinical trial
J Dermatolog Treat. 2014 Nov 26:1-19.

No universal consensus about optimal modality for treating the recalcitrant localized plaque psoriasis (RLPP).

To evaluate the immunological and clinical therapeutic effect of using Apitherapy in the treatment of RLPP.

Randomized fifty patients with RLPP received Apitherapy (n = 25) and placebo (n = 25) every week. Both treatments were injected into lesions at weekly intervals for a maximum of 12 treatments. Following up was 6 months later. Tumor necrosis factor-alpha (TNF-α) level was measured at pre-study and at 12th week.

A significant difference was found between the therapeutic responses of RLPP to Apitherapy and placebo group (P < 0.001). In the Apitherapy group, complete response was achieved in 92 % of patients. There was statistically significant decrease in TNF-α in Apitherapy group versus placebo group. No recurrence was observed in Apitherapy group.

Apitherapy is effective and safe treatment for recalcitrant localized plaque psoriasis, when other topical or physical therapies have failed.

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