Friday, July 4, 2014

Ethiopian Propolis Contains Unique Bio-active Compounds

The growing interest in propolis is generating numerous studies validating the importance of its unique composition. Though a majority of the compounds are consistently found in propolis worldwide, environmental sources play an essential role. This study discovered a unique compound - triterpenoids - due to the abundance of Acacia waxes and gums in the region. 

Characteristics and chemical compositions of propolis from Ethiopia
J Springer Plus; 2014 May

Introduction
Propolis is a sticky material mixed by honeybees to utilize it in protecting their hives from infection by bacteria and fungi. The therapeutic properties of propolis are due to its chemical composition with bio-active compounds; therefore, researchers are interested in studying its chemical constituents and biological properties. The main objective of this study is to determine the chemical compositions, characteristics and relative concentrations of organic compounds in the extractable organic matter of propolis samples collected from four different areas in Ethiopia.

Results
The propolis samples were extracted with a mixture of dichloromethane and methanol and analyzed by gas chromatography–mass spectrometry (GC-MS).The results showed that the total extract yields ranged from 27.2% to 64.2% (46.7 ± 19.1%). The major compounds were triterpenoids (85.5 ± 15.0% of the total extracts, mainly α-, β-amyrins and amyryl acetates), n-alkanes (5.8 ± 7.5%), n-alkenes (6.2 ± 7.0%,), methyl n-alkanoates (0.4 ± 0.2%), and long chain wax esters (0.3 to 2.1%).

Conclusion
The chemical compositions of these propolis samples indicate that they are potential sources of natural bio-active compounds for biological and pharmacological applications.

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