Royal Jelly is frequently referred to as a "Brain Booster" and this study takes it another step further by demonstrating improved memory and spatial learning, significant relevance for Alzheimer sufferers. Another important finding is the use of freeze-dried Royal Jelly, which eliminates obstacles such as the bitter taste and inconvenience of consuming fresh Royal Jelly...
Effect of
Royal Jelly on Spatial Learning and Memory in Rat Model of
Streptozotocin-Induced Sporadic Alzheimer's Disease
Adv BiomedRes, 2012;1:26
BACKGROUND:
It has been
recently demonstrated that Royal jelly (RJ) has a beneficial role on neural
functions. Alzheimer's disease (AD) is associated with impairments of learning
and memory. Therefore, the present study was designed to examine the effect of
RJ on spatial learning and memory in rats after intracerebroventricular
injection of streptozotocin (icv-STZ).
MATERIALS
AND METHODS:
Rats were
infused bilaterally with an icv injection of STZ, while sham rats received
vehicle only. The rats were feed with RJ-contained food (3% w/w) (lyophilized
RJ mixed with powdered regular food) or regular food for 10 days. Then spatial
learning and memory was tested in the rats by Morris water maze test.
RESULTS:
Results
showed that in icv-STZ group latency and path length were increased as compared
to sham group, also icv-STZ rats less remembered the target quadrant that
previously the platform was located; however, these were protected
significantly in STZ group that received RJ-containing food.
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